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Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) (C-Term) Peptide

MARCKS Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN979826

Aperçu rapide pour Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) (C-Term) Peptide (ABIN979826)

Antigène

MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

Origine

Humain

Source

  • 7
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Séquence

    KAAEEPSKVE EKKAEEAGAS AAACEAPSAA GPGAPPEQEA APAEEPAAAA

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-MARCKS Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

    Sujet

    The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

    Alias Symbols: 80K-L, FLJ14368, FLJ90045, MACS, PKCSL, PRKCSL

    Protein Interaction Partner: NMT1,CALM3,CTSB,NMT1,PKN1,PRKCA,PRKCB,TOB1,CALM2,CTSB,TOB1

    Protein Size: 332

    Poids moléculaire

    31 kDa

    ID gène

    4082

    NCBI Accession

    NM_002356, NP_002347

    UniProt

    P29966
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